IBRI science frontiers logo

IBRI Science Frontiers
3rd Annual Seminar Series

Learn More

Cyclic AMP Signaling in Islet Hormone Secretion: Old Questions and New Insights

Cyclic AMP Signaling in Islet Hormone Secretion: Old Questions and New Insights

Wednesday, September 08, 2021
9:00 AM - 10:00 AM

Presenter: Anders Tengholm, PhD

Organization: Uppsala University, Sweden

Dr. Anders Tengholm is a professor of secretion research at Uppsala University. His main field of interest concerns intracellular signaling that controls pancreatic islet hormone release and the mechanisms underlying the perturbed hormone secretion in diabetes.

Dr. Tengholm studied medicine in Uppsala and completed his PhD in 2000. Following a postdoc period at Stanford University, he moved back to his alma mater, where for the past 18 years he has led a research group that utilizes various live-cell imaging approaches to monitor the kinetics of a number of messengers, signaling proteins and exocytosis.

A particular focus has been how the spatio-temporal dynamics of ATP, Ca2+ and cAMP in b-cells contribute to the normal, pulsatile pattern of insulin secretion. Current research activities also include the stimulus-secretion coupling processes in glucagon- and somatostatin-releasing cells and the role of paracrine signaling within the islet for shaping the hormone release patterns. 

Register now