IBRI RESEARCH PUBLISHED: Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes

ABSTRACT The gene encoding eukaryotic initiation factor 5A (EIF5A) is found in diabetes-susceptibil... read more


IBRI RESEARCH PUBLISHED: Utilization of Electronic Health Records for the Assessment of Adiponectin Receptor Autoantibodies during the Progression of Cardio-metabolic Comorbidities

ABSTRACT Background: Diabetes is a complex, multi-symptomatic disease that drives healthcare costs ... read more


Developing Beta Cell Imaging Probes to Address Type 1 Diabetes Treatment

One of our newest postdoctoral fellows, Stephane Demine, recently shared with the Indiana Biosc... read more


IBRI RESEARCH PUBLISHED: Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia

Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disease with a prevalence of 1/... read more


How Does Exercise Really Increase Muscle Glucose Uptake?

Associate Research Fellow Carol Witczak, one of the newest members of the Indiana Biosciences R... read more


IBRI RESEARCH PUBLISHED: Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells

Adult human pancreatic beta cells are the “gold standard” for studies on diabetes pathog... read more


IBRI RESEARCH PUBLISHED: Hypusine biosynthesis in ß cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis

Deoxyhypusine synthase (DHPS) uses the polyamine spermidine to catalyze the hypusine modification of... read more


IBRI IN THE NEWS: Researchers working to understand why some patients with autoimmune diseases develop diabetes instead of arthritis

Autoimmune diseases are immune system disorders where the body’s immune system attacks its own... read more


Autoimmune Diseases: Why Diabetes rather than Arthritis?

INDIANAPOLIS, IND. -- Autoimmune diseases such as type 1 diabetes, rheumatoid arthritis, multiple sc... read more


Indiana life sciences organizations partner to launch new information source

Seven Indiana life sciences organizations today launched INscience, a one-stop shop for the sector&r... read more

 1 2 3 4 5  ... Last 

2018 Annual Report cover

The IBRI 2018 Annual Report is now available. The report theme is “Discovery With Purpose,” which is also the IBRI’s motto as it reflects the Institute’s commitment to translating scientific discovery into improved outcomes for patients.