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IBRI RESEARCH PUBLISHED: Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes
The gene encoding eukaryotic initiation factor 5A (EIF5A) is found in diabetes-susceptibil... read more
IBRI RESEARCH PUBLISHED: Utilization of Electronic Health Records for the Assessment of Adiponectin Receptor Autoantibodies during the Progression of Cardio-metabolic Comorbidities
Background: Diabetes is a complex, multi-symptomatic disease that drives healthcare costs ... read more
Developing Beta Cell Imaging Probes to Address Type 1 Diabetes Treatment
One of our newest postdoctoral fellows, Stephane Demine, recently shared with the Indiana Biosc... read more
IBRI RESEARCH PUBLISHED: Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia
Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disease with a prevalence of 1/... read more
How Does Exercise Really Increase Muscle Glucose Uptake?
Associate Research Fellow Carol Witczak, one of the newest members of the Indiana Biosciences R... read more
IBRI RESEARCH PUBLISHED: Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells
Adult human pancreatic beta cells are the “gold standard” for studies on diabetes pathog... read more
IBRI RESEARCH PUBLISHED: Hypusine biosynthesis in ß cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis
Deoxyhypusine synthase (DHPS) uses the polyamine spermidine to catalyze the hypusine modification of... read more
IBRI IN THE NEWS: Researchers working to understand why some patients with autoimmune diseases develop diabetes instead of arthritis
Autoimmune diseases are immune system disorders where the body’s immune system attacks its own... read more
Autoimmune Diseases: Why Diabetes rather than Arthritis?
INDIANAPOLIS, IND. -- Autoimmune diseases such as type 1 diabetes, rheumatoid arthritis, multiple sc... read more
Indiana life sciences organizations partner to launch new information source
Seven Indiana life sciences organizations today launched INscience, a one-stop shop for the sector&r... read more
The IBRI 2018 Annual Report is now available. The report theme is “Discovery With Purpose,” which is also the IBRI’s motto as it reflects the Institute’s commitment to translating scientific discovery into improved outcomes for patients.