Role of iPLA2b-Derived Lipids in T1D Development

Role of iPLA2b-Derived Lipids in T1D Development

Wednesday, August 11, 2021
10:30 AM - 11:30 AM

Presenter: Sasanka Ramanadham, PhD

Organization: The University of Alabama at Birmingham

Dr. Sasanka Ramanadham is a professor in the Department of Cell, Development and Integrative Biology at the University of Alabama at Birmingham.

Prior to joining the University of Alabama, he was a postdoctoral fellow at Washington University School of Medicine (WUSM). At WUSM, he worked with Dr. John Turk on lipid signaling in islet function. After his promotion to associate professor he focused on the contribution of lipid signaling to beta-cell death. Also during this time, his group identified a role for iPLA2b in this process and demonstrated that it plays a role in the development of T1D.

Dr. Ramanadham's recent focus has been on identifying the iPLA2b-derived lipids involved and countering their effects to mitigate diabetes development. Of special interest is how iDLs produced by beta-cells and immune cells work in concert to promote beta-cell death, leading to T1D.

Dr. Ramanadham received his undergraduate degree at McGill University in Montreal, Canada. He obtained his PhD at Texas Tech University in Lubbock, TX and completed a postdoctoral fellowship at the University of British Colombia, Vancouver, BC.

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