Disease, Systems, Pathways

Working to better understand the pathogenesis of diabetes

Flak Lab scientists working
DNA strand icon
Vials in a cold bath

Diabetes is our primary area of disease focus. We are working to better understand the pathogenesis of type 1 and type 2 diabetes. Our goal is to translate this knowledge into novel therapies, while also looking to expand into other diseases that share common systems and pathways.

Our diabetes researchers are catalysts for collaborations between academia and industry, and constantly strive to expand connections with other research centers and businesses in Indiana, throughout the US and around the world. These relationships will help us to create powerful discoveries that defeat disease, develop new tools to better understand illnesses and continue building a strong scientific network.

You can learn more about our disease, systems and pathways work and technologies here:

Back to Scientific Areas.


  • Indiana University-Purdue University Indianapolis School of Science
  • Indiana University School of Medicine
  • University of Notre Dame
Woman sits holding young sick girl on her lap in hospital room.

Pediatric Rare Diseases Research

Over 90% of rare diseases have no FDA-approved treatments

Pediatric Rare Diseases

“The primary way to treat neurofibromatosis 2 (NF2) hasn’t changed since I was in medical school. These kids, who live in our community, deserve more.”

D. Wade Clapp, MD
Chair of the Department of Pediatrics
Indiana University (IU) School of Medicine